Professional Invitations

January 1999 - Changing concepts in the ventilatory management of patients with ARDS. Surgery Department, Chestnut Hill Hospital, Philadelphia, PA.

August 2000 - Changing concepts in the ventilatory management of patients with ARDS. Dept. of Pulmonary Medicine, Hadassah Hebrew University Hospital, Jerusalem.

October 2000 - Modulation of Gene Expression in ARDS. Multidisciplinary critical care meeting. Hospital of the University of Pennsylvania, Philadelphia, PA.

November 2000 - Liver Physiology. Continued Medical Education, Kibbutz Maaleh Haamisha, Israel. Israel and European Societies of Anesthesia.

November 2000 - Panel on Liver Transplantation. Continued Medical Education, Kibbutz Maaleh Haamisha, Israel. Israel and European Societies of Anesthesia.

February 2001 - Anesthesiology Year in Review Panel. Featured speaker. Society of Critical Care Medicine Meeting, San Francisco.

January 2002 - New therapeutic Modalities in Sepsis. Dept. of Anesthesia and Critical Care Medicine. Sharee Zedek Hospital, Jerusalem.

January 2002 Adenoviral Mediated Expression of Heat Shock Protein in an Animal Model of ARDS. The Israel Society of Critical Care Medicine Annual Meeting, Jerusalem, Israel.

February 2002 - Artificial intelligence – applications in critical care medicine. Featured speaker. Society of Critical Care Medicine Meeting.

September 2002 - ARDS and blast injury – the Hadassah experience. Service d'anesthesie et reanimation polyvalente. Prof. Cathala. Hopitaux de Toulouse.

September 2002 - Adenoviral Transfer of HSP-70 into Pulmonary Epithelium. Service d'anesthesie et reanimation polyvalente. Prof. Cathala. Hopitaux de Toulouse.

November 2002 - “Protection of body organs at risk”. Featured speaker. 8th International Congress of Cardiothoracic and Vascular Anesthesia. Jerusalem.

November 2002  Artificial intelligence – applications in critical care medicine. Featured speaker. 8th International congress of Cardiothoracic and Vascular Anesthesia. Jerusalem.

July 2003 - Gene Therapy in ARDS, Planery lecture, Israel Society of Intensive Care Meeting, Tel-Aviv, Israel

October 2003 - Sepsis – Cellular Events. European Society of Intensive Care Medicine 16th Annual Congress, Amsterdam.

December 2003  Gene Therapy in ARDS, Planery lecture, Israel Society of Anesthesiologists, Tel-Aviv, Israel.

February 2004 - Effects of HSP-70 on the NF-kB Pathways Effects and Mechanisms of HSP-70 on Intracellular Pneumocyte Pathways. Society of Critical Care Medicine meeting, Orlando, Florida.

October 2004 - Mechanisms of cell repair after ventilator-induced lung  injury. 17th Annual congress European Society of Intensive Care Medicine. Berlin, Germany.

Awards and Honors

1995 - Distinction for Services as Chief Resident, Dept. of Anesthesiology and CCM, Hadassah, Hebrew University, Jerusalem

1987 – 1995  Fellow of the Center for Medical Education, Ben-Gurion University, Beer-Sheva, Israel

1983, 1984, 1985 - Dean's Distinction List, School of Medicine, Israel Institute of Technology - Technion, Haifa

2002 - The Hadassah Women Zionist Organization Prize for Outstanding Research Achievement 2002.

Industry Consultant

1990 – 1991 Development of the Pharmacist Computer Program (automated drug prescription computer program).

2000 – 2001 Safety Data Monitoring Board Member - Difetur Trial - a new drug for the treatment of hypotension. Meditor Ltd., Israel.

2001- 2003  Scientific Advisory Board Member, MTR-105, Meditor Ltd., Israel.

Patents

U.S. Patent Application "A Method of Preventing Acute Pulmonary Cell Injury"  No. 10/150,054 submitted on May 16, 2002

Bibliography

1) Original Research Papers in Peer Reviewed Journals:

1. Meiri, H., Weiss, Y., Lallkin, A., Collins, I.: Distribution and possible abnormality in antigenic composition of sodium channels in peripheral axons of dystrophic mice. Brain Research 384:355-361, 1986.

2. Weiss, Y., Rabinovitch, M., Cahaner, Y., Noy, D., Siegman-Igra, Y.: Prevalence of Hepatitis B virus markers among hospital personnel in Israel: it's correlation with some risk factors. J. Hosp. Infect. 26:211-218, 1994.

3. Weiss, Y.G., Cotev, S., Drenger, B., Katzenelson, R.: Patient management systems in anesthesia: an emerging technology. Can J Anaesth 42:914-921, 1995.

4.  Efrat, R., Oppenheim, A., Weiss, Y., Kedari, A.: Epidural analgesia for postoperative pain in infants and children. Harefuah 5:304-307, 1996 (Hebrew).

5. Pizov, R., Cohen, M., Weiss, Y., Segal, E., Cotev, S., Perel, A.: PEEP-induced hemodynamic changes are reflected in the arterial pressure waveform. Crit Care Med 24 (8): 1381-1387, 1996.

6. Koganov, Y., Weiss, Y.G., Elami, A., Oppenheim, A., Pizov, R.: Positive end-expiratory pressure increases pulmonary venous vascular resistance in patients after coronary artery surgery. Crit Care Med 25 (5): 767-772, 1997.

7. Shenkman Z., Elami A., Weiss Y.G., Glantz L., Milgarter E., Drenger B., Burrows F.A., Shir Y.: Preliminary Report: Cerebral protection using retrograde cerebral perfusion during hypothermic circulatory arrest. Can J Anaesth 44 (10): 1096-1101, 1997.

8. Pizov R., Oppenheim A.., Eidelman L.A., Weiss Y.G., Sprung C.L., Cotev S. Helium versus oxygen for tracheal gas insufflation during mechanical ventilation. Crit Care Med 26 (2):290-295; 1998.

9. Reider E., Sherman Y., Weiss Y, Liebergal M., Pizov R  Alveolar macrophages fat stain in early diagnosis of fat embolism syndrome. Israel journal of Medical Sciences 33:654-658; 1997.

10. Shenkman Z., Shir Y., Weiss Y.G., Bleiberg B., Gross D. The effect of cardiac surgery on early and late pulmonary functions. Acta Anaesthesiologica Scandinavica 41:1193-1199; 1997.

11. Pizov R. Oppenheim-Eden A. Matot I. Weiss YG. Eidelman LA. Rivkind AI. Sprung CL. Blast lung injury from an explosion on a civilian bus. Chest 115(1):165-72, 1999.

12. Weiss YG, Oppenheim-Eden A, Gilon D, Sprung L, Muggia-Sullam M, Pizov R. Systolic pressure variation in hemodynamic monitoring after severe blast injury.  J Clin Anesth 11:132-135, 1999.

13. Weiss YG, A. Bouwman, B.Gehan, N. Raj, C.S. Deutschman. Cecal ligation and double puncture impairs heat shock protein 70 (hsp-70) expression in the lungs of rats. Shock 13:19-23, 2000.

14. Weiss YG, G. Merin, , E. Koganov, A. Ribo, A. Oppenheim-Eden, B. Medalion, M. Peruanski, Reider, J. Bar-Ziv, C.W.Hanson,, R. Pizov. Post cardiopulmonary bypass hypoxemia: a prospective study on incidence, risk factors and clinical significance. J Cardioth Vasc Anesth 14:506-513, 2000.

15. Pizov R., Weiss Y.G., Oppenheim-Eden A., Glickman H., Goodman S., Koganov Y., Barak V., Merin G., Kramer M.R. High oxygen exacerbates cardiopulmonary bypass induced lung injury. J Cardioth Vasc Anesth 14:519-523, 2000.

16. Weiss Y.G., A. Maliar, L.A. Eidelman, Y. Berlatzky, C.W. Hanson III, C.S. Deutschman, G. Zajicek. Computer assisted physiologic monitoring and stability assessment in vascular surgical patients undergoing general anesthesia. J Clin Monit Comput 16:107-113, 2000.

17. Weiss Y. G., Bellin L., Kim P. K., Andrejko K. M., Haaxma C. A., Raj N., Furth E., Deutschman C. S. Compensatory Hepatic Regeneration After Mild, But Not Fulminant, Intraperitoneal Sepsis. Am J Physiol 280:G968-G973, 2001.

18. Weiss Y.G., Tazelaar J., Gehan B.,

Bouwman A., Christofidou-Solomidou M., Yu Q-C., Raj N., Deutschman C.S. Adenoviral vector transfection into the pulmonary epithelium after cecal ligation and puncture (CLP) in rats. Anesthesiology. 95:974-982; 2001.

19. Weiss Y.G., Maloyan A., Tazelaar J., Raj N., Deutschman C.S.  Adenoviral Transfer of HSP-70 into Pulmonary Epithelium Improves Histology and Outcome in Experimental Acute Respiratory Distress Syndrome. J. Clin Invest. 110:801-806, 2002.

20. Levin PD, Worner TM, Sviri S, Goodman SV, Weiss YG, Einav S, Weissman C, Sprung CL. Intensive care outflow limitation--frequency, etiology, and impact. J Crit Care 2003 Dec;18(4):206-11.

21. Shamir M.Y., Weiss Y. G., Willner D., Mintz Y., Sprung C.L., Weissman C. The response of an anesthesiology department to multiple casualty terror events. Anesth. Analg. (in Press).

More in PubMed

2) Clinical Observations

1. Weiss Y., Gozal Y., Braverman I., Gozal D. Cardiac arrest during rigid bronchoscopy. Cah Anesthesiol 1997, 45:443-444.

2. Oppenheim A., Pizov R., Pikarsky A., Weiss Y.G., Zamir G., Sprung C.L., Rivkind A. Tension pneumoperitoneum after blast injury: dramatic improvement in ventilatory and hemodynamic parameters after surgical decompression. J Trauma 44: 915-917; 1998.

3. Oppenheim-Eden A, Matot I, Perouanski M, Weiss YG, Pollak A, Pizov R, Schetz M. Myocardial function improvement after hemofiltration in a septic patient. J Cardioth Vasc Anesth 13:484-489; 1999.

3) Editorials

1. Weiss Y.G., Deutschman C.S.: Modulation of Gene Expression in Critical Illness: A New Millennium or a Brave New World? Crit. Care Med., 28:3078-3079, 2000.

4) Non-Peer-Reviewed Papers

1. Eidelman, L. A., Weiss, Y.G., Sprung, C.L.: Adjunctive therapy for pediatric  infections. D. Engelhard, MI Marks, D.Branski (eds): Pediatric Infectious Diseases; Pediatr Adolesc Med. Basel, Karger 4:69-78, 1993.

2. Weiss, Y., Edelman, L., Sprung, C.: Corticosteroids in sepsis and in shock following sepsis. Harefuah 127: 188-190, 1994. (Hebrew).

3. Gilon, D., Weiss, Y.G., Gotsman, M.S., Rein, A.J.J.T.: Transesophageal echocardiography in the operating room: New applications. Harefua; 12:576-579, 1995. (Hebrew).

4. Weiss, Y.G., Sprung, C.L.: Patient data management systems in critical care Current Opinion in Critical Care 2:187-192, 1996.

5. Weiss, Y.G., Pollak A., Gilon, D.: Transesophageal echocardiography in critical care medicine. Current Opinion in Critical Care 3: 232-237, 1997.

6. Weiss Y.G., Deutschman C.S.: The role of fiberoptic bronchoscopy in airway management of the critically ill patient. Critical Care Clinics, 16:445-451, 2000.

7. Dahan E., Orbach S., Weiss Y. G. Fluid Management In Trauma. Internat. Anesthesiology Clinics 38:141-147; 2000.

8. Willner D., Bloom A., Goodman S., Weiss Y.G. Splanchnic Tissue Perfusion in Patients with Circulatory Failure. Contemporary Crit Care. November 2004

9. Shamir MY., Willner D., Weiss YG. Use of hypertonic fluid replacement solutions in critical care. Contemporary Crit Care. (in Press).

5) Chapters in Books

1. Cotev, S., Eidelman, L.A., Weiss, Y.G.: Ischemic microvascular failure in severe head injury. A. Gullo (Ed.) Anesthesia, pain, intensive care and emergency medicine; Critical care medicine, Springer; pp: 161-167, 1995.

2. Weiniger C., Ginosar Y., Sprung C., Weiss Y.G.: Arterial and pulmonary artery catheters. Parrillo J.E., Dellinger R.P. (eds): Critical Care Medicine: Principles of Diagnosis and Management in the Adult. Mosby, Second edition, pp: 36-63.

3. Orbach S., Weiss Y.G., Deutschman C.S.: The patient with sepsis or systemic inflammatory response syndrome. Murray M.J., Coursin D.B., Pearl R.G., and Prough D.S. (eds): Critical Care Medicine – Perioperative Management, Lippincott/ Raven, Second Edition 2002, pp: 601-615.

4. G. Steuer, S. Goodman, P. Levin, S. Einav, B. Minz, C.L. Sprung, A. I. Rivkind, C. Weissman, Y.G. Weiss. Acute lung injuries among survivors from Suicide bomb attacks. J. Shemer, Y. Shoenfeld (eds): Terror and Medicine - Medical aspects of biological, chemical and nuclear terrorism.  Pabst Science Publishers, April 2003.

7) Abstracts

1. Lehmann, D., Kofmel, B.A., Weiss, Y.G. Momentary EEG state and classes of subjective experiences During “day dreaming”. University Hospital, Zurich, Switzerland. Presented at the first Swiss EEG meeting, Zurich, 1989.

2. Weiss Y.G., P.D. Levin, G. Zajicek. Computer assisted monitoring of physiologic parameters during  anesthesia. Presented at the 17th international congress of the Israel society of anesthesiologists, Tel-Aviv, Israel, 1996.

3. Weiss Y.G., R. Pizov, V. Barak, E. Kaganov, M.R. Kramer, G. Merin. The effect of oxygen on cardiopulmonary bypass lung injury. Presented at the 17th international congress of the Israel society of anesthesiologists, Tel-Aviv, Israel, June 1996.

4. Weiss Y.G., Koganov E., Openheim A., Medalion B., Peruanski M., Raider, E., Bar-Ziv J., Merin G., Pizov R. Post cardiopulmonary bypass hypoxemia: incidence, risk factors, and clinical significance. Presented at the ASA 1997. Anesthesiology 87: A127; 1997.

5. Weiss Y.G., W.C. Hanson, G. Zajicek. Computer assisted analysis of physiologic parameters in anesthesia. Accepted for presentation at the American Medical Informatics Association 1998 Spring Congress May 29, 1998.

6. Hanson C.W., Y. Weiss, F. Frash, C. Marshall, B.E. Marshall. A Fuzzy control strategy for postoperative volume resuscitation. Anesthesiology, 89(supp):A475, 1998.

7. Hanson C.W., Y. Weiss, F. Frash, C. Marshall, B.E. Marshall. Neurofuzzy analysis of hemodynamic data. Anesthesiology, 89(supp):A474, 1998.

8. Weiss Y.G., J. Chen , C.S. Deutschman Heat shock protein (hsp) expression in the lungs after cecal ligation and double puncture in rats. Crit Care Med 27(supp):A129, 1999.

9.  Weiss Y.G., A. Maliar, L.A. Eidelman, C.S. Deutschman, C.W. Hanson III,G. Zajicek. Health state magnitude- integrating physiologic parameters. Crit Care Med 27(supp): A113, 1999.

10. Gehan B, Bouwman AR, Weiss YG, Deutschman CS. Mixed venous and bronchoalveolar lavage (BAL) fluid predicts systemic inflammatory response syndrome (SIRS) in patients undergoing photodynamic therapy (PDT). Shock 11(supp):22, 1999.

11. Bouwman AR, Weiss YG, Gehan B, Christofidou-Solomidou M, Tazelaar J, Deutschman CS. Cecal ligation and double puncture (2CLP) induces acute lung injury (ALI) / adult respiratory distress syndrome (ARDS) in rats. Shock 11(supp):39, 1999

12. Weiss YG, Bouwman AR, Gehan B, Tazelaar J, Deutschman CS. Adenoviral vector transfection into the pulmonary epithelium after cecal ligation and puncture (CLP) in rats. Presented in part at the Shock Society meeting San-Antonio, TX 1999 (Shock 11(supp):52, 1999) and before the Anesthesiology Journal Symposium at the ASA meeting, Dallas, TX  1999 (Anesthesiology 91: A1388; 1999).

13. Weiss Y.G., Eden-Openheim A., Perouansky M., Siegal T., Weissman C. Loss of heart rate variability in patients undergoing osmotic blood-brain barrier disruption (BBBD). Presented at the ASA meeting  in San-Francisco 2000.

14. Perouansky M., Ronin L., Eden‑Openheim A., Siegal T. Weiss Y.G. Effect of Therapeutic Blood‑Brain Barrier Disruption (BBBD) on Cerebrospinal Fluid Homeostasis. Presented at the ASA meeting in San-Francisco 2000.

15. Weiss Y.G., Tazelaar J., Raj N., Deutschman C.S.  Adenoviral Vector Heat Sock Protein 70 (HSP-70) Transfection Into The Pulmonary Epithelium. Presented at the Shock Society Meeting, June 2001, Marco Island, Fl

16. Weiss Y.G., Maloyan A., Tazelaar J., Raj N., Deutschman C.S.  Adenoviral Transfer of HSP-70 into Pulmonary Epithelium Improves Histology and Outcome in Experimental ARDS. Presented at the Society of Critical Care Medicine (SCCM) Meeting, San-Diego, CA, January 2002.

17. Weiss Y. G., Maloyan A., Raj N., Deutschman C. S. Adenoviral-Mediated Pulmonary Expression Of Hsp-70 Limits NF-kB Activation. Presented at 2002 Shock Society Meeting, Big-Sky, Montana, June 2002 (Shock, 17:A11; 2002.)

18. Weiss Y.G., A. Maloyan, Z. Blomberg, N. Raj, C. S. Deutschman Adenoviral-Mediated Pulmonary Expression Of Hsp-70 Limits Nf-Kb Activation. Association of University Anesthesiologists 50th Annual Meeting, Milwaukee, Wisconsin, May 2003.

19. Weiss Y. G., Z. Bromberg, A. Maloyan, N. Raj, C.S. Deutschman.  Enhanced Adenoviral-Mediated Pulmonary Expression Of Heat Shock Protein-70 (Hsp-70) After Cecal Ligation Double Puncture (2clp) Preserves Fatty Acid Synthase Activity. Twenty-Sixth Annual Conference On Shock Phoenix, Arizona-- June 7 - 10, 2003.

Research Grants

Competitive

1996 - Computer Assisted Monitoring of Physiologic Parameters in Anesthesia and Critical Care Medicine. Scientist - Israel Ministry of Health, Chief Investigator. (NIS10,000)

2000 - Adenoviral Vector Heat Shock Protein Transfection Into The Pulmonary Epithelium After Cecal Ligation And Puncture In Rats. The University of Pennsylvania - Hadassah-Hebrew University Fund for Gene Therapy Research - Chief Investigator (US$25,000).

2000 - Adenoviral Vector Heat Shock Protein Transfection Into The Pulmonary Epithelium After Cecal Ligation And Puncture In Rats. The Israel Health Ministry, General Scientist - Chief Investigator. (US$25,000)

‏

2001 - CORTICUS – Use of low dose steroids in sepsis. European community supported multiple center study. Principal Investigator for Hadassah Medical Center (50,000 Eur).

2002 - Heat Shock Protein -70 (HSP-70) Expression in the Whole Lung and in Alveolar Epithelial Cell Cultures - Effect and Mechanisms of Action. The Israel Health Ministry, General Scientist - Chief Investigator. (US$25,000).

2003 - Adenoviral Transfer of HSP-70 into Pulmonary Epithelium Improves Histology and Outcome in Experimental Acute Respiratory Distress Syndrome.  HWZOA Award (US$15,000)

2003 - Adenoviral Transfer of HSP-70 into Pulmonary Epithelium Improves Histology and Outcome in Experimental Acute Respiratory Distress Syndrome.  Ministry of Health - General Scientist (No. 5304) (US$ 20,000)

2003 - Heat Shock Protein -70 (HSP-70) Expression in the Whole Lung and in Alveolar Epithelial Cell Cultures - Effect and Mechanisms of Action. The Israel Science Foundation (No. 586/03) (US$ 30,000/year for 4 years)

Non-Competitive

2000 - Prevention of Acute Respiratory Distress Syndrome (ARDS) with Inhaled Steroids - Preliminary Study.  Supported by Glaxo-Welcome Inc. – Drugs and placebo inhalers  as well as spacers provided free of charge.

2000 - Pathohysiology of Myocardial Injury and Cardiac Mortality in Critically Ill patients in the Non-coronary ICU:  Can it be prevented? Giora Landesberg M.D., D.Sc. - Department of Anesthesiology & C.C.M., Morris Mosseri M.D. - Department of Cardiology, Yoram Weiss M.D., Charles Sprung M.D., J.D. , Charles Weissman M.D. - Department of Anesthesiology & C.C.M. The H.G. Berman Grant dedicated to studying the Physiology of the Heart (US$ 10,000).

2003 - Respiratory patterns and postoperative analgesia- interpretation of non-linear patterns.  Supported by Oridion Medical 1987 Ltd.- Computer and electronic equipment. This study is performed in collaboration with Prof. Jay Fineberg, The Racah Institute of Physics, The Hebrew University, Jerusalem.

M.D. Thesis Supervisor

A.  M. Tuibeneshlag - 1995. Influence of PEEP on the pulmonary vascular resistance.

B.  A. Asa – 1996. Computer Assisted Monitoring of Physiologic Parameters During Anesthesia for Abdominal Aortic Aneurysm Surgery.

C. A. Tuttnauer - Present - Respiratory patterns and postoperative analgesia- interpretation of non-linear patterns. This study is performed in collaboration with Prof. Jay Fineberg, The Racah Institute of Physics, The Hebrew University, Jerusalem.

Instructor Basic Science Component of Residency (Madaei Yesod)

2002 - Lev Ronin, MD., Effect of Therapeutic Blood‑Brain Barrier Disruption (BBBD) on Cerebrospinal Fluid Homeostasis. To be published.

2002 - Esther Dahan, MD., Prevention of Acute Respiratory Distress Syndrome (ARDS) with Inhaled Steroids - Preliminary Study. Data analysis to be performed. Terminated.

2003 - Daphna Willner, MD., Respiratory patterns and postoperative analgesia- interpretation of non linear patterns. This study is performed in collaboration with Prof. Jay Fineberg, The Racah Institute of Physics, The Hebrew University, Jerusalem. On going.

2004 - Helena Plotnikova, MD., Use of the cone and Plate analyzer to assess platelet function in patients with septic shock. To be published.