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Prof. David BenEzra

 

 

Former  Director of

Pediatric Ophthalmology Unit and the

Immuno-Ophthalmology Service

Ein-Karem, Jerusalem

 

 

A graduate of the Medical School in Jerusalem (1971) and a PhD in Immunology (1969) of the Hebrew University in Jerusalem.

 

Finished residency in Ophthalmology at Hadassah University Hospital in 1976. Held additional appointments as follows:

 

Visiting Scientist and a senior clinical staff member at the National Eye Institute during 1976-78 and 1983-84;

 

Distinguished Visiting Scholar at New York Beth Israel Medical Center in 1988;

 

Visiting Professor at the Ophthalmology Department, Creteil, France (1999);

 

Professor of the Universities and Hospital of Paris, France (2001).

 

Since 1986, Director of Pediatric Ophthalmology Unit and the Immuno-Ophthalmology and Uveitis Service and Head of Laboratory for Ocular Angiogenesis and Immuno-Ophthalmology at Hadassah Hospital, Jerusalem, Israel.

 

Appointed Associate Professor of Ophthalmology (1981) and Professor of Ophthalmology in 1986, the Hebrew University of Jerusalem.

 

Certified American Board of Ophthalmology since 1978.

 

Fellow of the American Academy of Ophthalmology since 1979.

 

Visiting Professor and Invited Speaker

 

1976    National Eye Institute, Bethesda, Maryland, USA

1976    Retina Foundation, Harvard Medical School, Boston, Massachusetts, USA

1977    Department of Ophthalmology, Buffalo, New York, USA

1977    Department of Ophthalmology, Yale University, New Haven, CT. USA

1978    Department of Ophthalmology, University of Illinois, Chicago, Illinois, USA

1978    Department of Ophthalmology, University of Florida, Gainesville, Florida,    USA

1979    Wilmer Eye Institute, Johns Hopkins University, Baltimore, Maryland, USA

1980    Department of Ophthalmology, University Hospital, Freiburg, Germany

1980    Department of Ophthalmology, University Hospital, Essen, Germany

1981    National Eye Institute, Bethesda, Maryland, USA

1982    Department of Ophthalmology, University Hospital, Oulu, Finland

1983    National Eye Institute, Bethesda, Maryland, USA

1983    Proctor Foundation, University of California, San Francisco, California, USA

1984    Jules Stein Eye Institute, University of California, Los Angeles, California, USA

1985    Departments of Ophthalmology and Internal Medicine, Hospital de la Salpetriere, Paris, France

1985    Department of Ophthalmology, University of the Witwatersrand, Johannesburg, South Africa

1987    Department of Ophthalmology, University of Lausanne, Lausanne, Switzerland

1988    The Netherlands Ophthalmic Research Institute, Amsterdam, Holland

1988    Department of Ophthalmology, Medical Academy, Gdansk, Poland

1988    Department of Ophthalmology, Mount Sinai Hospital, New York, USA

1989    National Institute of Health, Bethesda, Maryland, USA

1989    Department of Ophthalmology, Taegu, South Korea

1989    Department of Ophthalmology, Kwanju, South Korea

1989    Thailand Ophthalmological Society, Bangkok, Thailand

1990    Department of Ophthalmology, University of Alicante, Alicante, Spain

1991    Moorfields Eye Hospital, London, England

1992    Department of Ophthalmology, Escuala Paulistica, Sao Paulo, Brazil

1993    Department of Ophthalmology, Prague, Czech Republic and Kosice, Slovak Republic

1993    Department of Ophthalmology, Munchen, Germany

1994    Department of Ophthalmology, University of Lausanne, Lausanne, Switzerland

1994    Department of Ophthalmology, Kansai Medical University, Osaka, Japan

1995    Department of Ophthalmology, Hospital Sao Joao, Porto, Portugal

1995    Special Lecturer, 8th Annual CIBA Vision Symposium, Tokyo, Japan

1996    Department of Ophthalmology, Hopital des Specialites, Rabat, Morocco

1996    Faculty of Medicine, Department of Ophthalmology, Casablanca, Morocco

1997   73rd Congress of the Spanish Ophthalmological Society

3rd Forum Ophthalmologicum, Brno, Czech Republic

Symposium on Behcets Disease, Coimbra, Portugal

 

2001   Congress of Spanish Ophthalmological Society, Barcelona, Spain

 

2001-2002 Appointed Professor of the Universities and Hospitals in Paris, France

 

2001 – Present           Associate Scientist, INSERM, France

 

2001-2002  Appointed Professor of the Universities and Hospitals in Paris, France

 

2001 – 2009  Visiting  Scientist, INSERM, France

 

2004 – 2005 Professor, University Paris Ouest, France

 

Prizes and Awards

 

1977    Recipient of Dr. Yassky Award for Achievements in Ophthalmology, New York, November 1977

 

1979    Recipient of the Hebrew University Medical School Faculty Prize for outstanding research in Ophthalmology

 

1987    Recipient of the Hadassah Medical Relief Association Distinguished Service Award

 

1988    New York, Beth Israel Medical Center Distinguished Visiting Scholar for 1988

 

1988    Guest of Honor, Polish Academy of Sciences, and Guest Speaker, Annual Meeting of the Polish Ophthalmological Society, Gdansk, Poland

 

1988    Recipient of Alcon Research Institute’s Award for outstanding contributions in the field of Vision Research ($50,000 award)

 

1991    Guest of Honor, Portuguese Ophthalmological Society Meeting,      Lisbon, Portugal

 

1992    Guest of Honor, Brazilian Ophthalmological Society Meeting, Sao Paulo, Brazil

 

1992    Guest of Honor, Royal Australian College of Ophthalmologists, Sydney, Australia

 

1993    Guest of Honor, International Symposium on Clinic and Therapy of Uveitis, Lisbon, Portugal

 

1995    Guest of Honor, Japan Ophthalmological Society Yearly Symposium, Tokyo and Kyoto, Japan

 

1995    First Regner Lecturer, S:t Eriks Eye Hospital, Stockholm, Sweden

 

1996    Guest of Honor, Annual Greek Ophthalmological Society Meeting, Thessaloniki, Greece

 

1997    Guest of Honor, Annual Spanish Ophthalmological Society, Granada, Spain

 

1998    Guest of Honor, Annual Moroccan Ophthalmological Society, Casablanca, Morocco

 

1999     Recipient of Honorary Professor of the Miguel Hernandez University in Alicante, Spain

 

2002    Guest of Honor, 106th Annual Meeting Japanese Ophthalmological Society, Japan

 

2006     Guest of Honor, Annual Meeting, Philippines Academy of Ophthalmology.

 

2006     Guest of Honor, Annual Meeting, Argentine Society of Ophthalmology.

 

 

 

International Activities

 

- Past President, International Ocular Inflammation Society

- President, Mediterranean Ophthalmological Society

- Co-Chairman, International Panel on: “Guidelines for the Diagnosis and

Treatment of Intraocular Inflammation”

- Member, New York Academy of Sciences

- Member, International Strabismological Association

- Member, Association of Research in Vision and Ophthalmology

- Member, International Ocular Inflammation Society

- Chairman, International Panel on: “Guidelines for the Diagnosis and Treatment of Conjunctivitis”

- Member of the International Scientific Study Group on Behcet’s Disease

- Member of the Lions Club International Research Committee, American Diabetes Association

- Member of the International Committee for the Classification of Retinoblastoma

- Program Committee “JERMOV”, Joint European Research Meetings in Ophthalmology and Vision

- Member, International Members Subcommittee, ARVO

 

Scientific Activity

 

Papers (from 2000 – 2006)

 

Cela E, BenEzra D: Aniridia and Down Syndrome. Journal of Pediatric Ophthalmology & Strabismus, 37: 369-370, 2000

 

BenEzra D, Cohen E: Cataract Surgery in Children with Chronic Uveitis, Ophthalmology, 107: 1255-1260, 2000

 

BenEzra D. Cohen E, Karshai I: Phakic Posterior Chamber IOL for the Correction of Anisometropia and Treatment of Amblyopia. American Journal of Ophthalmology, 130: 292-296, 2000

 

BenEzra D, Cohen E, Maftzir G: Patterns of Intraocular Inflammation in Children. Bulletin de la Societe Belge d’Ophtalmologie, 279: 35-8, 2001

 

Behar-Cohen FF, BenEzra D,Einmahl S, Gurny R: Challenges of Intraocular Drug Delivery. European Pharmaceutical Review, p.35-39, 2001

 

Anteby I, Cohen E, Anteby E, BenEzra D: Ocular manifestations in children born after in-vitro-fertilization. Archives of Ophthalmology, 119: 1525-1529, 2001

 

Mauget-Faysse M, Quaranta M, Francoz N. BenEzra D: Incidental retinal phototoxicity associated with ingestion of photosensitizing drugs. Graefes Archives of Clinical Experimental Ophthalmology,  239: 501-508, 2001.

 

Anteby I, Cohen E, Karshai I, BenEzra D: Unilateral persistent hyperplastic primary vitreous: course and outcome. Journal of the American Association for Pediatric Ophthalmology & Strabismus 6: 92-99, 2002.

 

Alio J, BenEzra D: Intraocular Inflammation. Is there any Light at the end of the Tunnel? Highlights of Ophthalmology 30: 2-7, 2002

 

Alio J, BenEzra D: Intraocular Inflammation Guidelines. Investigation of the patient prior to Therapy in Anterior (ASII) or Posterior segment intraocular inflammations (PSII).  Highlights of Ophthalmology 30: 8-10, 2002    

 

M. Mauget-Faysse, L. Kodjikian, M. Quaranta, D. BenEzra, C. Trepsat, F. Mion, F. Megraud: Role de l’Helicobacter pylori dans la Chorioretinopathie sereuse centrale et l’epitheliopathie retinienne diffuse Journal French Ophtalmology, 25, 10, 1021-1025, 2002.

 

Alio JL, Chipont E, BenEzra D, Fakhry MA: International Ocular Inflammation Society, Study Group of Uveitic Cataract Surgery. Comparative performance of intraocular lenses in eyes with cataract and uveitis Journal of Cataract & Refractive Surgery 28: 2096-2108, 2002.

 

BenEzra D: In-vitro fertilization and retinoblastoma. Commentary. Lancet 361: 273-274, 2003.

 

Anteby I, Isaac M, BenEzra D: Hereditary Subluxated lenses: Visual performances and long-term follow-up after surgery. Ophthalmology 110:1344-1348, 2003

 

Berdugo M, Valamanesh F, Andrieu C, Klein C, BenEzra D, Courtois Y, Behar-Cohen F: Delivery of antisense oligonucleotide to the cornea by iontophoresis. Antisense Nucelic Acid Drug Development 13:107-114, 2003

 

Enk CD, Anteby I, Abramson N, Amer R, Amit Y, Bergshtein-Kronhaus T, Cohen E, Greenberg Z, Jonas F, Maayan S, Marva E, Strauss U, BenEzra D:  Onchocerciasis among Ethiopian immigrants in Israel. Israel Medical Association Journal  5:485-488, 2003.

 

Enk CD, Gardlo K, Ruzicka T, BenEzra D: Onchocerciasis. Hautarzt 54:513-517, 2003 (German)

 

Bourges JL, Gautier SE, DElie F, Bejjani RA Jeanny JC, Gurny R, BenEzra D, Behar-Cohen FF: Ocular drug delivery targeting the retina and retinal pigment epithelium using polylactide nanoparticles. Investigative Ophthalmology & Visual Science 44: 3562-3569, 2003.

 

Bourges JL, Savodelli M, Dighiero P, Assouline M, Pouliquen Y, BenEzra D, Renard G, Behar-Cohen F: Recurrence of keratoconus characteristics: a clinical and histologic follow-up analysis of donor grafts. Ophthalmology 110: 1920-1925, 2003

 

Halhal M, Renard G, Courtois Y, BenEzra D, Behar-Cohen F.: Iontophoresis: from the lab to the bedside. Experimental Eye Research 78:751-7, 2004.

 

Bourges JL, Valamanesh F, Torriglia A, Jeanny JC,  Savodelli M, Renard G, BenEzra D, de Kozak Y, Behar-Cohen F: Cornea graft endothelial cells undergo apoptosis by way of an alternate (caspase-independent) pathway. Transplantation 78: 316-323, 2004.

 

BenEzra D, Cohen E, Maftzir G: Uveitis in children and adolescents. British Journal of Ophthalmology September 2004 (in press)

 

Halhal M, Renard G, Courtois Y, BenEzra D, Behar-Cohen F.: Iontophoresis: from the lab to the bedside. Experimental  Eye Research 78:751-7, 2004.

 

Jean-Louis Bourges, Fatemeh Valamanesh, Alicia Torriglia, Jean-Claude Jeanny,  Michèle Savoldelli, Gilles Renard, David BenEzra, Yvonne de Kozak, Francine Behar-Cohen:  Cornea graft endothelial cells undergo apoptosis by way of an alternate (caspase-independent) pathway.  Transplantation 78: 316-323, 2004.

 

Riad Antoine Bejjani, David BenEzra, Hagit Cohen, Jutta Rieger, Charlotte Andrieu, Jean-Claude Jeanny, Gershon Golomb, Francine F. Behar-Cohen:  Nanoparticles for gene delivery to retinal pigment epithelial cells. Molecular Vision 11: 124-132, 2005.

 

Nadia Normand, Fatemeh Valamanesh, Michèle Savoldelli, Frédéric Mascarelli, David BenEzra, Yves Courtois, Francine Behar-Cohen.: VP22 light controlled delivery of oligonucleotides to ocular cells in vitro and in vivo. Molecular Vision 11:184-191, 2005.

 

BenEzra D, Cohen E, Maftzir G:  Uveitis in children and adolescents. British Journal of Ophthalmology 89: 444-448, 2005

 

I. Habil, E. Cohen. I. Karshai, F. Behar-Cohen, D. BenEzra:  Spontaneous involution of autologous lenses and phacoanaphylaxis reaction in Stickler syndrome.  British Journal of Ophthalmology 89: 1532-1533, 2005

 

Berdugo M, Andrieu-Soler C, Doat M, Courtois Y, BenEzra D and Behar-Cohen F.: Downregulation of ISR-1 expression causes inhibition of corneal angiogenesis.  Investigative Ophthalmology and Visual Science 46; 4072-4078, 2005.

 

Bloquel C, Bejjani R. Bigey P, Bedioui F, Doat M, BenEzra D, Scherman D, Behar-Cohen F.:  Plasmid electrotransfer of eye ciliary muscle: principles and therapeutic efficacy using hTNF-alpha soluble receptor in uveitis.  FASEB J. 20:389-391, 2006.

 

F. Behar-Cohen, D. BenEzra, G. Soubrane, L. Jonet, J.C. Jeanny:  Krypton laser photocoagulation induces retinal vascular remodeling rather than choroidal neovascularization (CNV).  Experimental Eye Research 83:263-275, 2006.

 

Books

 

Forrester JV, Okada A, BenEzra D, Ohno S:  Posterior Segment Intraocular Inflammation, Guidelines.  Kugler Publications, The Netherlands, 1998. pp. 1-184.

 

BenEzra D:  OCULAR INFLAMMATION: Basic and Clinical Concepts.  Martin Dunitz Publishers, England, 1999. pp.1-512.

 

BenEzra D, Ohno S, Alio J, Secchi A (eds):  Anterior Segment Intraocular Inflammation, Guidelines.  Martin Dunitz Publishers, 2000, pp. 1-156

 

BenEzra D: Ocular Surface Inflammation – Guidelines for Diagnosis and Treatment. Highlights of Ophthalmology, Panama. 2003, pp. 1-266

 

BenEzra D:  Blepharitis and Conjunctivitis. Guidelines for Diagnosis and Treatment. Glosa Publishers, Barcelona, Spain 2006

 

Member of Editorial Board of Scientific Journals

 

Investigative Ophthalmology and Visual Sciences    

Current Eye Research

International Ophthalmology Clinics

European Journal of Ophthalmology

Ocular Immunology and Inflammation

 

Served as Guest Editor for the Journal of Cataract and Refractive Surgery, special issue on “Pediatric Cataract”.

 

Clinical Interest

 

- Pediatric Ophthalmology

- Immuno-Ophthalmology and Uveitis

- Genetic Therapy

- Refractive Surgery.




 



            
     
 


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