Endocrinology and Metabolism Service
Hadassah-Hebrew University Medical Center
Ein-Karem, Jerusalem.
Tel: (+972) 2 6776788
Fax: (+972) 2 643 7940
E-mail: rivkap@md.huji.ac.il
Education
M.D. - Hebrew University Medical School, Jerusalem, 1987
Internal Medicine Residency - Hadassah Hebrew University Medical Center, 1987-1991
Geriatric Fellowship - Division on Aging, Harvard Medical School, Beth Israel Hospital
Boston, USA, 1991- 1993
Endocrinology Fellowship - Beth Israel Hospital, Boston, USA 1992-1994
Employment
1994 Associate in Medicine, Beth Israel Hospital, Boston, USA
1994-2003 Senior Physician, Department of Medicine, Hadassah University hospital on Mount Scopus
2003–present Senior Endocrinologist, Hadassah Hebrew University Medical Center, Jerusalem
Academic Appointments
1994 - Instructor in Medicine, Harvard Medical
School, Boston
1994-2000 - Lecturer in Medicine, Hebrew University, Jerusalem
2000-present - Senior Lecturer in Medicine, Hebrew University, Jerusalem
Clinical Specialty
● Osteoporosis, Bone and Mineral metabolism
● Geriatric Endocrinology
● General Endocrinology
Areas of Research Interest
● Role of IL-10 in bone physiology
● Mechanisms of bone loss in inflammatory bowel disease and in biliary cirrhosis
● Clinical use of biochemical markers of bone turnover in osteoporosis
● Association between sequence variants in the estrogen receptor alpha gene and clinical syndromes including osteoporosis, coronary artery disease and dementia
● Genetics of osteoporosis
List of Publications
Rosen H, Dresner Pollak R, Moses A, Rosenblatt M, Zeind JA, Clemens DJ Greenspan SL. Specificity of urinary excretion of cross-linked N-telopeptides of
type 1 collagen as a marker of bone turnover. Calcif Tissue Int 54:26‑29, 1994
Dresner-Pollak R, Rosenblatt M. Blockade of osteoclast-mediated bone resorption through occupancy of the integrin receptor: A potential approach to the therapy of osteoporosis. J Cellular Biochem 57:1-8, 1994
Chorev M, Dresner Pollak R, Eshel Y, Rosenblatt M. Approach to discovering novel therapeutic agents for osteoporosis based on integrin receptor blockade. Biopolymers 37:367-375, 1995
Dresner Pollak R, Yang Qui-Ming, Behar V, Nakamoto C, Chorev M, Rosenblatt. In vivo studies with [Nle 8,18, D-Trp 12, Tyr 34] bPTH(7-34)NH2: A potent PTH antagonist in thyroparathyroidectomized rats. J Bone Miner Res 11:1061‑1065, 1996
Dresner-Pollak R, Ginsberg G, Cohen A, Stessman J. Characteristics of falls in 70 years old in Jerusalem. Isr J Med Sci 32:625-628, 1996
Dresner-Pollak R, Parker RA, Poku M, Thompson J, Seibel MJ, Greenspan SL. Biochemical markers of bone turnover reflect femoral bone loss in elderly women. Calcif Tissue Int 59:328-333, 1996
Greenspan SL, Dresner-Pollak R, Parker R.A., London D, Ferguson L. Diurnal variation of bone mineral turnover in elderly men and women. Calci Tissue Int 60:419‑423, 1997
Dresner-Pollak R, Karmelli F, Eliakim R, Ackerman Z, Tabb K, Rachmilewitz D. Femoral neck osteopenia in patients with inflammatory bowel disease. Am J Gastroenterol 93:1483-1490, 1998
Dresner-Pollak R, Mayer M, Hochner-Clenikier D. The change in bone -specific alkaline phosphatase as a predictor for bone mineral density response to hormonal replacement therapy in early postmenopausal women. Calcif Tissue Int 66:104-107, 2000
Dresner-Pollak R, Karmelli F, Eliakim R, Ackerman Z, Rachmilewitz D. Increased urinary N-telopeptide cross-linked type 1 collagen predicts bone loss in patients with inflammatory bowel disease. Am J Gastroenterol 95:699‑704, 2000
Dresner-Pollak R, Idelson M, Doron D, Bejarano I, Pollak A, Blumenfeld A. The C677T mutation in the methylenetetrahydrofolate reductase gene (MTHFR) and vascular dementia JAGS 48: 1-5, 2000
Dresner-Pollak R, Rachmilewitz E, Goldfarb A. Bone Mineral Metabolism in adults with beta-thalassemia major and intermedia. Br J of Haematol 111:902-907, 2000
Bar-On E, Sagiv S, Floman Y, Katz K, Dresner-Pollak R, Maayan C. Orthopedic manifestations of Familial Dysautonomia. J Bone Joint Surgery 11:1563-1570, 2000
Dresner-Pollak R, Friedlander Y, Pollak A, Idelson M, Bejarano I, Blumenfeld A. Ethnic differences in the frequency of the C677T mutation in the methylenetetrahydrofolate reductase (MTHFR) gene in healthy Israeli populations. Genetic Testing 4:309-311, 2000
Dresner-Pollak R, Blumenfeld A, Bejarano-Achache I, Idelson M, Celinker Hochner D. The BsmI vitamin D receptor gene polymorphism in Israeli populations and in perimenopusal and osteoporotic Ashkenazi women. The Am J Nephrol, 21:185-188, 2001
Safadi R, Galun E, Ashur Y, Eid A, Melhem A. Jurim O, Polak R, Ilan Y. Bone mineral density after liver transplantation. Transplantation Proc. 33:2950-1, 2001
Ackerman Z, Weinreb M, Amir G, Dresner Pollak R. Bone Mineral Metabolism and histomorphometry in rats with cholestatic liver disease. Liver 22:166-172, 2002
Maayan C, Bar On E, Foldes A.J, Geusndheit B, Dresner Pollak R. Bone mineral density and metabolism in familial dysautonomia. Osteoporosis Int 13:429-433, 2002
Pollak A, Rokach A, Blumenfeld A, Rosen LJ, Resnik L, Dresner Pollak R. Association of estrogen receptor alpha gene polymorphism with the angiographic extent of coronary artery disease. Eur Heart J 25:240-245, 2004
Weinreb M, Dresner Pollak R, Ackerman Z. Experimental cholestatic liver disease through bile-duct ligation in rats results in skeletal fragility and impaired osteoblastogenesis. J Hepatol 40:385-390, 2004
Rosenmann H, Meiner Z, Dresner-Pollak R, Kahana E, Aladjem Z, Grenader T, Wertman E, Abramsky O. Lack of association of interleukin-1 beta polymorphism with Alzheimer’s disease in the Jewish population. Neuroscience Letters, 363:131-133, 2004
Dresner Pollak R, Gelb N, Rachmilewitz D, Karmeli F, Weinreb M. Interleukin 10–deficient mice develop osteopenia, decreased bone formation and mechanical fragility of long bon bones. Gastroenterology, 2004 (in press)
Chapters in books
Dresner-Pollak R, Sheehan M, Gerhart T. N. Osteoporosis and hip fractures in the elderly. In: Wei JY, Sheehan M (ed). Geriatric Medicine: a case-based manual, Oxford University Press, pp. 105-113, 1997.
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