Hadassah Ein Karem's Department of Medicine is a tertiary care center for internal medicine, consisting of 3 inpatient wards, a day care unit and a medical intensive care unit.

It houses the departments of Gastroenterology, Endocrinology, Nephrology and Pulmonology, and includes units specializing in Atherosclerosis, Geriatrics, Liver Diseases, Diabetes, Rheumatology, Clinical Immunology and Allergy,  and Clinical nutrition.

The department provides state of the art medical care to patients from all parts of the country, while engaging in advanced clinical and bio-medical research through a variety of centers of excellence and in under and post-graduate teaching.

The Department of Medicine seeks to foster an interdisciplinary approach that combines healing, teaching and research under one department umbrella.